課程大綱：生物醫學大數據揭秘培訓
Week 1: Introduction and Overview of Bioinformatics Platforms and Resources
Introduction to the Course -Interview with Bioinformatics at Georgetown University Medical Center.
Dr. Robert Clarke, Dean for Research, at Georgetown University Medical Center
Biomedical Informatics: Enabling Research and Health Care. Interview with Dr.
Subha Madhavan, Director of the Innovation Center for Biomedical Informatics (ICBI) at Georgetown University
Biomedical Big Data: Enabling Personalized Medicine. Interview with Dr. John Marshall, Chief, Hematology and Oncology,
Lombardi Comprehensive Cancer Center, Georgetown University Medical Center internationally recognized medical oncologist
Week 2: Translational Research and Big DataTranslational Research
Translational Research Lecture, Part 1 Part I
Translational Research Lecture, Part 2 Part II
The Cancer Genome Atlas
The Cancer Genome Atlas Lecture
The Cancer Genome Atlas Demo
The Cancer Genome Atlas Exercise
Introduction to G-DOC
G-DOC Lecture
G-DOC Demo
G-DOC ExerciseWeek 3: DNA and Big DataDNA Copy Number
DNA Copy Number Lecture
DNA Copy Number Demo
DNA Copy Number Exercise
Genome Sequencing
Genome Sequencing Lecture, Part 1
Genome Sequencing Lecture, Part 2
Genome Sequencing Demo
Genome Sequencing ExerciseWeek 4: RNA and Big DataGene Expression
Gene Expression Lecture
Gene Expression Demo
Gene Expression Exercise
MicroRNA
MicroRNA Lecture
MicroRNA Demo
MicroRNA ExerciseWeek 5: Proteins and Big Data Part IProteomics
Protein Sequences Lecture
Protein Interactions Lecture
Mass Spec Proteomics, Lecture
Proteomics ExerciseWeek 6: Proteins and Big Data Part IIProteomics (Continued)
Data Sharing, Metadata, Data Formats
Ontologies
Proteomics Demo, Part 1
Proteomics Demo, Part 2
Proteomics Demo, Part 3
Proteomics ExerciseWeek 7: Systems Biology and Big DataSystems Biology
Systems Biology Lecture, Part 1
Systems Biology Lecture, Part 2
Systems Biology and Data Analysis Demo
Systems Biology Exercise
Week 8: Perspectives from the Field and Course Conclusion
Perspectives from the Field
Regulatory issues Issues related Related to biomedical Biomedical big Big dataData. Sheila Zimmet,
JD, Senior Associate Vice President for Regulatory Affairs, and Ashley Carver, JD,
Deputy Conflicts Officer and Regulatory Affairs Associate, Georgetown University Medical Center.
Enabling Everyone to Share and Use Public Datasets. Interview with Dr. Ben Busby,
genomics Genomics outreach Outreach coordinator Coordinator at the National Center for Biotechnology Information (NCBI)
Interview withCancer Moonshot. Dr. Jerry Lee, Deputy Director, Center for Strategic Scientific Initiatives,
Office of the Director, National Cancer Institute, National Institutes of Health
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